Linezolid-Resistant Staphylococcus epidermidis, Portugal, 2012
نویسندگان
چکیده
To the Editor: Linezolid is a therapeutic option for skin and soft tissue infections and pneumonia caused by multidrug-resistant gram-positive bacteria (e.g., Staphylococcus spp.), which occur at higher rates in Portugal than in other European countries (www.ecdc.europa.eu/en/
منابع مشابه
Composite SCCmec Element in Single-locus Variant (ST217) of Epidemic MRSA-15 Clone
1. Mendes RE, Deshpande LM, Costello AJ, Farrell DJ. Molecular epidemiology of Staphylococcus epidermidis clinical isolates from U.S. hospitals. Antimicrob Agents Chemother. 2012;56:4656–61. http://dx.doi.org/10.1128/AAC.00279-12 2. de Almeida LM, Lincopan N, Araújo MR, Mamizuka EM. Dissemination of the linezolid-resistant Staphylococcus epidermidis clone ST2 exhibiting the G2576T mutation in t...
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OBJECTIVES To report an outbreak of colonization with linezolid-resistant Staphylococcus epidermidis in an intensive therapy unit (ITU). METHODS An outbreak of colonization with linezolid-resistant S. epidermidis affecting 16 patients in an ITU was investigated using PFGE. Environmental and staff screening was carried out as part of the investigation. Usage of linezolid in the hospital and in...
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Staphylococcus epidermidis is the most prevalent species of coagulase-negative staphylococci (CNS). It accounts for over 65% of all staphylococci isolated from samples. In recent years the increasing relevance of CNS as pathogens is evident, mainly causing bacteraemia and prosthetic device infection. Linezolid, being an effective antibiotic against this pathogen, and due to its ease of use and ...
متن کاملSequential linezolid-resistant Staphylococcus epidermidis isolates with G2576T mutation.
We report on an analysis of sequential isolates of Staphylococcus epidermidis from cultures of blood obtained from a patient with acute myeloid leukemia while the patient was receiving linezolid treatment. All 12 isolates had a linezolid MIC of 32 microg/ml. A 420-bp domain V region of the 23S rRNA gene from all isolates was amplified, and their nucleotide sequences were determined. A G2576T mu...
متن کاملPolyphyletic emergence of linezolid-resistant staphylococci in the United States.
Since the year 2000, linezolid has been used in the United States to treat infections caused by antimicrobial-resistant Gram-positive cocci. At present, linezolid-resistant (Linr) Staphylococcus aureus and Staphylococcus epidermidis strains are rare and the diversity of their genetic backgrounds is unknown. We performed sequence-based strain typing and resistance gene characterization of 46 Lin...
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عنوان ژورنال:
دوره 20 شماره
صفحات -
تاریخ انتشار 2014